Medical Policy

Subject: Radiofrequency and Pulsed Radiofrequency Treatment of Trigger Point Pain
Document #: SURG.00125 Current Effective Date:    09/27/2017
Status: Reviewed Last Review Date:    08/03/2017


This document addresses the treatment of trigger point pain (also known as myofascial pain syndrome) with radiofrequency (RF) or pulsed radiofrequency (PRF). RF and PRF are procedures that apply high-frequency, alternating current to tissues via a probe inserted through the skin. This document does not address RF and PRF of non-myofascial tissue (e.g. nerves and joints) or transcutaneous RF treatment techniques.

Note: Please see the following related document(s) for additional information:

Position Statement

Investigational and Not Medically Necessary:

Radiofrequency (RF) and pulsed radiofrequency (PRF) treatment of trigger points are considered investigational and not medically necessary.


To date, there is little evidence supporting the efficacy and safety of RF and PRF therapy in myofascial tissue. A small number of case-studies, and one case-series, have been published with evidence of moderate therapeutic effect. Limitations across published literature on RF and PRF in trigger-point therapy include small sample sizes, lack of a control group and the mechanism of therapeutic effect remains unknown.

Tamimi and colleagues (2009) reported the use of PRF for the treatment of myofascial trigger points and scar neuromas in 9 participants who were treated over an 18-month period. A total of 8 out of the 9 participants had a 75 to 100% reduction in their pain following PRF treatment at 4 weeks post-op. A total of 6 out of the 9 (67%) participants experienced 6 months to greater than 1 year of pain relief. The participants had no complications related to PRF. The authors concluded that PRF could be a treatment modality for myofascial trigger point pain; however, further studies and evaluation of this treatment approach are required.

Lee and colleagues (2011) also found that the use of PRF for focal pain in non-nervous tissue has shown favorable effects. In their case report, a person with posterior cervical pain and headaches was described with a painful point in the posterior neck area. Nerve blocks guided by radiologic imaging were first performed; although the headaches improved after 5 days, the posterior neck pain continued. In contrast, following PRF treatment, the individual rated posterior neck pain as 0 on a scale of 0/10. The individual reported continued pain relief of headache and posterior neck pain during a 5-month follow-up. A caveat of this publication was that the participant's pain-relieving point differed from 'trigger point' pain and was thought to most likely reside in the subcutaneous tissue rather than myofascial tissue. The authors acknowledged that despite the shortcomings in this report the positive response seen in this case from PRF treatment in non-nervous tissue warrants further investigation.

Park and colleagues (2012) also published a case report on an individual with myofascial pain originating in the trapezius and the surrounding muscles. The individual was treated with multiple therapies that provided only transient pain relief. PRF was performed on both trapezius muscles. One week post-procedure, the individual reported significant pain relief, which was subsequently sustained for 3 months. The authors concluded that further research is needed to explain the sustained effect of PRF on myofascial tissue, as well as to demonstrate the efficacy and safety of this treatment modality.

In a prospective case series, Niraj (2012) followed 12 participants with cervicothoracic or abdominal myofascial pain. All participants were non-responders to multiple treatments and ultimately received ultra-sound guided PRF. A total of 9 of the 12 participants (75%) reported 40% or better pain relief 6 months post-procedure. Similar to the aforementioned reports, the author concluded that randomized controlled trials are needed to establish safety, efficacy and therapeutic mechanism of PRF.


Muscle injury or repetitive muscle stress may lead to the development of trigger points. Trigger point pain most often occurs in the muscles that maintain body posture such as the neck, shoulder and pelvic girdle. This results in regional, persistent pain and decreased range of motion in the affected muscles. Physical examination may reveal a nodule of muscle fiber. Palpation of this nodule may produce pain over the trigger point or cause the pain to radiate to another area with a local twitch response (Alvarez, 2002).

Treatments for trigger point pain vary. Initially, conservative management such as activity modification in combination with oral medication, such as analgesics, steroids and muscle relaxants, may provide pain relief. Physical and chiropractic therapy are often utilized to increase range of motion (Alvarez, 2002). Injections of anesthetics, with or without steroids, have been used to provide pain relief when conservative therapy is unsuccessful (Alvarez, 2002; Niraj, 2012).

RF and PRF are procedures used to treat affected tissues using a high-frequency alternating current. RF energy in the form of continuous heat is transmitted to the tip of a needle probe which is inserted through the skin, often guided by x-ray or ultrasound to ablate targeted tissues. PRF differs from RF, in that PRF uses pulsed heat energy, allowing tissue cooling between energy pulses. It is theorized, that pulsed energy eliminates the potential for ablation of tissue and that it is the exposure to a rapidly changing electrical field alone, not tissue ablation, which induces sufficient cellular change to provide a therapeutic effect (Byrd, 2008).


Ablation: The destruction or removal of tissue.

Focal pain: Pain that is easily identified as being specific to a single location.

Myofascia: The fibrous tissue that encloses and separates layers of muscles.

Nodule: A small solid collection of tissue.

Trigger points: Hyperirritable areas in the skeletal muscle that are associated with palpable nodules in taut bands of muscle fibers; stimulation or compression may elicit local tenderness, referred pain, or a local twitch response.


The following codes for treatments and procedures applicable to this document are included below for informational purposes. Inclusion or exclusion of a procedure, diagnosis or device code(s) does not constitute or imply member coverage or provider reimbursement policy. Please refer to the member's contract benefits in effect at the time of service to determine coverage or non-coverage of these services as it applies to an individual member.

When services are Investigational and Not Medically Necessary:
When the code describes a procedure indicated in the Position Statement section as investigational and not medically necessary.

20999 Unlisted procedure, musculoskeletal system, general [when specified as radiofrequency or pulsed radiofrequency treatment of trigger points]
ICD-10 Diagnosis  
  All diagnoses

Peer Reviewed Publications:

  1. Alvarez DJ, Rockwell PG. Trigger points: diagnosis and management. Am Fam Physician. 2002; 65(4):653-660.
  2. Byrd D, Mackey S. Pulsed radiofrequency for chronic pain. Curr Pain Headache Rep. 2008; 12(1):37-41.
  3. Lee J, Yoon K, Kim K, Mi Yoon D. Pulsed radiofrequency treatment of pain relieving point in a soft tissue. Korean J Pain. 2011; 24(1):57-60.
  4. Niraj G. Ultrasound-guided pulsed radiofrequency treatment of myofascial pain syndrome: a case series. Br J Anaesth. 2012; 109(4):645-646.
  5. Park C, Lee Y, Kim Y, et al. Treatment experience of pulsed radiofrequency under ultrasound guided to the trapezius muscle at myofascial pain syndrome. Korean J Pain. 2012; 25(1):52-54.
  6. Tamimi MA, McCeney MH, Krutsch J. A case series of pulsed radiofrequency treatment of myofascial trigger points and scar neuromas. Pain Med. 2009; 10(6):1140-1143.

Focal Pain
Pulsed Radiofrequency (PRF)
Trigger Point

The use of specific product names is illustrative only. It is not intended to be a recommendation of one product over another, and is not intended to represent a complete listing of all products available.

Document History
Status Date Action
Reviewed 08/03/2017 Medical Policy & Technology Assessment Committee (MPTAC) review. Updated References section.
Reviewed 08/04/2016 MPTAC review. Updated Rationale and References sections. Removed ICD-9 codes from Coding section.
Reviewed 08/06/2015 MPTAC review. Updated Rationale and References sections.
Revised 08/14/2014 MPTAC review. Revised Title, and Investigational and Not Medically Necessary statement with the removal of "ablation". Updated Description, Rationale, Background, References, and Index sections.
Reviewed 08/08/2013 MPTAC review. Updated Description, Rationale, and Background sections.
Reviewed 08/09/2012 MPTAC review. Rationale and References updated.
New 08/18/2011 MPTAC review. Initial policy development.